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Treating Macular Degeneration in the future may only require an eye drop instead of an injection!

May 22, 2017

Researchers at Birmingham University have developed an eye drop that could treat wet AMD. 

Why hasn’t this been done yet?

Because getting large drug molecules (i.e Lucentis & Avastin) all the way to the back of the eye is a challenge. Given the many layers of the cornea, the conjunctiva, the sclera, the blood-retinal barrier, drop dilution from tears….you could say there are a few obstacles to drug penetration.
So how did they do it?

CPP = cell penetrating peptides.

Through the magic of biochemistry, scientists found that attaching CPP within a drop aids in drug delivery.

What did the study find?

Their anti-VEGF drop with CPP (dosed daily) was just a efficacious as a single intravitreal injection in reducing areas of CNV in mouse, rat, and pig eyes.

The authors state, “Efficacious self-administered drug application by eye drop would lead to a significant reduction in adverse outcomes and health care costs compared with current treatments”.

I picked this up from 2020 Glance

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A new “get the red out” for your eyes….It’s coming!

May 15, 2017

Is there something besides Visine I can use to get the red out?

Ask me again in 7 months.
B&L filed a new drug application for their OTC topical vasoconstrictor, Luminesse.
If approved, this will be the first OTC product developed with brimonidine tartrate for the treatment of ocular redness. In the six clinical studies, the drug was found to be highly efficacious and safe with low risk of tachyphylaxis (tolerance or loss of effectiveness) and rebound congestion, which are both common to currently available OTC redness reliever eye drops.
The FDA will announce if they approve/deny Luminesse in December.

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I was blinded by my contact lens

April 12, 2017

http://www.bbc.co.uk/news/magazine-39568781

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Good Vision Prevents Dementia…..

April 5, 2017

Decreased Near-Vision Function In Older Patients May Increase Risk For Later Dementia, Study Suggests.

Medscape Share to FacebookShare to Twitter (4/4, Brauser) reports, “Decreased near-vision function in older patients may increase the risk for later dementia,” researchers concluded . After analyzing data on some “7700 participants older than age 65 years,” investigators found that “those with moderate-to-severe near-vision loss at baseline were significantly more likely to develop dementia 12 years later than those who did not have any loss of function.” The findings were presented at the International Conference on Alzheimer’s and Parkinson’s Diseases and Related Neurological Disorders (AD/PD) 2017.

 

This is a good reason to see your eye doc….Hopefully me on a yearly basis. Even if you don’t see any changes in your vision. Let us decide together if there are changes, before you stop reading due to an inability!timthumb

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New One Day Toric from CooperVision available in the U.K……so soon it will be in the USA. 

March 24, 2017

https://www.opticianonline.net/news/coopervision-range-expands-for-astigmatism-patients
New one day toric to compete with BioTrue one day toric and Clarity one day toric contacts. I wonder when it will cross the Atlantic Ocean to New York?

Alcon has mentioned that they will have a new one day toric in their Total 1 daily platform. 

This proves to me that dailies are in, monthlies and bi-weeklies are on the downswing!

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A Fifth Contact Lens Company?

March 16, 2017

http://finance.yahoo.com/news/medical-device-company-visioneering-technologies-230200961.html
Is this enough to compete the the Big 4?

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NYTimes: Patients Lose Sight After Stem Cells Are Injected Into Their Eyes

March 15, 2017

https://www.nytimes.com/2017/03/15/health/eyes-stem-cells-injections.html?smprod=nytcore-ipad&smid=nytcore-ipad-share

What to look for in a con job on your eyes.

1) experimental procedure done on both eyes at the same time.

2) probably a lot of money for the procedure ( like multiple thousands of dollars)

3) treatment on the retina, but Not by a retina surgeon!

Before you do any experimental treatment, ask more than one doctor to see of it is an accepted practice, or something out in left field!

Questions about eye procedures? Call or email!